Organonitrogen Compounds
Apexbio Technology LLC Hexamethonium Bromide 55-97-0 1g
Hexamethonium Bromide (CAS 55-97-0) is a bis-quaternary ammonium compound that acts as a selective antagonist of neuronal nicotinic acetylcholine receptors (nAChRs) located in autonomic ganglia By competitively inhibiting synaptic transmission at these receptors Hexamethonium Bromide effectively blocks ganglionic neurotransmission without significant effects on muscarinic receptors or neuromuscular junctions This property makes it a valuable tool in pharmacological studies investigating autonomic nervous system function and the physiological roles of ganglionic nAChRs in various experimental models
Medchemexpress LLC Hexamethonium Bromide | 55-97-0 | 99.91% | 1 ML
Hexamethonium Bromide is a non-selective ganglionic nicotinic-receptor (nAChR) antagonist with mixed competitive and noncompetitive activity. It possesses anti-hypertensive properties and can attenuate sympathetic activity and blood pressure in spontaneously hypertensive animal models.
- Non-selective ganglionic nicotinic-receptor antagonist
- Exhibits mixed competitive and noncompetitive activity
- Possesses anti-hypertensive properties
- Attenuates sympathetic activity and blood pressure
- Effective in spontaneously hypertensive animal models
Medchemexpress LLC Hexamethonium Bromide | 55-97-0 | 99.9% | 100 G
Hexamethonium Bromide is a non-selective ganglionic nicotinic-receptor antagonist (nAChR) that exhibits mixed competitive and noncompetitive activity. Known for its anti-hypertensive properties, it can effectively attenuate sympathetic activity and blood pressure in spontaneously hypertensive animal models. This product is presented as a high-purity, white to off-white solid.
- Non-selective ganglionic nAChR antagonist
- Demonstrates mixed competitive and noncompetitive activity
- Attenuates sympathetic activity and blood pressure
- Suitable for research in neurological, cardiovascular, and immune system diseases
- Available as a white to off-white solid with 99.9% purity
Medchemexpress LLC Mdeg-541 | C35H38N4O6S2 | 5 MG
MDEG-541 is a potent MYC-MAX degrader and a PROTAC, derived from the MYC-MAX dimerization inhibitor 10058-F4 (derivative 28RH) and Thalidomide (HY-14658). It exhibits antiproliferative activity and reduces the expression of GSPT1, MYC, GSPT2, and PLK1 proteins. It also decreases the expression of MYC in a dose-dependent manner and inhibits cell viability in HCT116 and PSN1 cells.
- Potent MYC-MAX degrader
- PROTAC based on 10058-F4 derivative and Thalidomide
- Shows antiproliferative activity
- Decreases expression of GSPT1, MYC, GSPT2, PLK1 protein
- Inhibits cell viability in HCT116 and PSN1 cells
Selleck Chemical LLC Decamethonium Bromide S4072-50mg
Decamethonium Bromide is a nicotinic AChR partial agonist and neuromuscular blocking agent
Apexbio Technology LLC Decamethonium Bromide 541-22-0 5g
Decamethonium Bromide (CAS 541-22-0) is a bis-quaternary ammonium compound targeting nicotinic acetylcholine receptors (nAChRs) at the neuromuscular junction It is designed to bind and activate muscle-type nAChRs thereby inducing sustained depolarization and neuromuscular blockade Decamethonium Bromide exerts its biological activity primarily through partial agonist-mediated depolarization block of these receptors preventing normal muscle contractions Based on these pharmacological properties Decamethonium Bromide holds research potential in the evaluation of neuromuscular blockers and in studies elucidating receptor-channel function in neuromuscular transmission
Sigma Aldrich Fine Chemicals Biosciences Decamethonium bromide crystalline | 541-22-0 | MFCD00011779 | 5G
Decamethonium bromide crystalline | Mol Wt: 418.29 | 541-22-0 | MFCD00011779 | 5G
